Sunday, December 11, 2011

carcinogenic effect and smoking

"We know that the carcinogenic effect is the square of one dose (Higginson, 1988). You double the dose, you square its impact. But we also know that it rises to the fourth power of time; that is to say if you double the time of exposure, that time interval has a fourth power exponential impact. If we take a 60-year-old person who has been smoking a pack of cigarettes a day for 20 years, that person actually has one-tenth the chance of getting lung cancer compared to a 60 year old person smoking one-half pack a day for 40 years."
-Jay H. Lehr, Ph.D. "Toxicological Risk Assessment Distortions"

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